Ghazal Shariatpanahi; Rezvan Hashemi; Mahsa Asadabadi; Nava Shirzadi; Nazgol Sadat Haddadi; Safoura Shakoei
Abstract
Background: Acne is a common chronic inflammatory skin disease predominantly occurring during adolescence; this condition adversely affects a person’s self-esteem and can be associated with metabolic disorders. This study aimed to investigate the prevalence of metabolic syndrome and its components ...
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Background: Acne is a common chronic inflammatory skin disease predominantly occurring during adolescence; this condition adversely affects a person’s self-esteem and can be associated with metabolic disorders. This study aimed to investigate the prevalence of metabolic syndrome and its components in adolescent girls with acne compared to a control group. Materials and Methods: In this cross-sectional study,105 adolescent girls aged 12-18 years were assigned to either the acne (case; n=55) or control group (n=50). The case group was selected from the Dermatology Department of a general hospital in Tehran, Iran, between January and August 2017. Acne lesions were confirmed and graded by a dermatologist. Clinical and biochemical parameters were evaluated for all participants. Results: The prevalence of metabolic syndrome in patients with and without acne was 18.2% and 14%, respectively. As a result, metabolic syndrome was not correlated with acne in adolescent girls (P=0.561). In addition, the mean body mass index (P=0.89), waist circumference (P=0.62), mean systolic and diastolic blood pressures (P=0.57 and 0.62, respectively), fasting blood sugar (P=0.59), total cholesterol, and low-density lipoprotein cholesterol levels were comparable between the studied groups (P>0.05). Moreover, triglyceride levels were significantly lower in the acne group (P=0.028), whereas this group featured a higher level of high-density lipoprotein cholesterol (P=0.02). However, the logistic regression results showed that none of the measured lipids were associated with acne. Conclusion: The findings indicated that metabolic syndrome and its components (representing metabolic imbalance) were not correlated with acne in adolescent girls.
Safoura Shakoei; Nazanin Nasri; Ghazal Shariatpanahi; Rezvan Hashemi
Abstract
Background: Acne is a chronic inflammatory skin disease and a cosmetic problem with considerable emotional and psychological side effects and symptoms, such as pain and pruritus. Some controversies exist concerning the involvement of dietary factors, including glycemic load (GL), ...
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Background: Acne is a chronic inflammatory skin disease and a cosmetic problem with considerable emotional and psychological side effects and symptoms, such as pain and pruritus. Some controversies exist concerning the involvement of dietary factors, including glycemic load (GL), in the pathogenesis of acne. Accordingly, we aimed to determine the role of GL and anthropometric measures in acne development among girls aged 12-18 years in Tehran, Iran.Methods: In this cross-sectional study, 99 girls (45 girls without acne and 54 girls with acne) aged 12 18 years completed a threeday food record. Anthropometric measures, such as height, weight, waist circumference, and body mass index (BMI), were also assessed. Additionally, an expert dermatologist scored the severity of acne, and then, anthropometric measures and GL were examined in the groups.Results: The results showed no significant difference in dietary GL, height, weight, BMI, and waist circumference between the groups. Furthermore, the severity of acne was not significantly associated with GL.Conclusion: The present results did not confirm the association between acne and dietary carbohydrates, including GL. However, further research can contribute to determination of the effect of diet on acne and its severity.